A drug called "Tranexamic acid"is an antifibrinolytic drug that has anti-inflammatory and anti-allergic effects, as well as a pronounced hemostatic effect in bleeding that is associated with increased fibrinolysis. This preparation is based on inhibition of the plasminogen activator and plasmin, inhibition of the formation of active peptides and kinins, which are directly involved in inflammatory and allergic reactions. In addition, a remedy such as Tranexamic acid significantly prolongs thrombin time. As for the peculiarities of the pharmacokinetics of this antifibrinolytic drug, after intake, about 30-50% of its initial dosage is absorbed, with the largest plasma concentrations observed in one hundred and eighty minutes after use. The antifibrinolytic effect in the tissues persists for fifteen to seventeen hours, and in plasma for seven to eight hours after the application of Tranexamic Acid. The price for this product is about 1,300 rubles, and you can buy it in almost every pharmacy.
An antifibrinolytic drug is available in the form oftablets of two hundred and fifty or five hundred milligrams, in the form of a solution for injection, and also in the form of a solution intended for oral administration. All of the listed dosage forms are excellent for treating and preventing bleeding, triggered by an increase in total fibrinolysis. For example, a drug called Tranexamic acid is often prescribed, with malignant neoplasms of the prostate or pancreas, leukemia, surgical interventions on the chest, liver diseases. Manual separation of the afterbirth and postpartum hemorrhage are also included in the list of indications for prescribing. In addition, the drug "Tranexamic acid" should be used for hematuria, angioedema, allergic dermatitis, eczema, toxic and medicinal rash, urticaria. In addition, this drug is actively prescribed for pharyngitis, laryngitis, tonsillitis, stomatitis, nasal, uterine and gastric bleeding, tooth extraction in patients diagnosed with hemorrhagic diathesis. Also, such a remedy as Tranexamic acid, with monthly, differing abundant secretions, helps.
As for the specifics of the application anddosage of the medicine, then in each case they are set individually, proceeding from this or that clinical situation. However, as a rule, at a time, not more than 1-1.5 grams is allowed inside. In this case, the frequency of use is two to four times a day, and the duration of treatment is from three to fifteen days. A single dose for intravenous administration is 10-15 mg / kg.
The main contraindications to useThis means are such conditions as subarachnoid hemorrhage, thromboembolic syndrome, renal failure, impaired color perception and deep vein thrombosis. In addition, do not use this drug in case of increased individual sensitivity or pregnancy. Side effects associated with taking this antifibrinolytic drug are manifested in the form of dizziness, drowsiness, hypotension, tachycardia, weakness and pain in the chest.